Cardiovascular risk assessment in adolescents with systemic lupus erythematosus: biomarkers related to lipid metabolism
نویسندگان
چکیده
Introduction Juvenile systemic lupus erythematosus (JSLE) is a chronic, autoimmune and multisystem disease. Adult patients with SLE have an elevated risk of premature atherosclerosis and myocardial infarction. Dyslipidemia is a risk factor for the development of future chronic diseases and is associated with disease activity, corticosteroids use (CTC), renal impairment, among other factors. Other biochemical markers have been proposed for identification of cardiovascular risk, among them the protein components of lipoproteins (apolipoproteins Apo) and enzyme related to cardiovascular risk (paraoxonase PON).
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